Seeking a motivated Postdoctoral Researcher in Dr. Popel's laboratory in the Departments of Biomedical Engineering and Oncology, The Johns Hopkins School of Medicine. The successful candidate will join a team that combines computational, experimental and clinical researchers using computational systems biology and quantitative systems pharmacology (QSP) to discover mechanisms of immunotherapies and conduct virtual clinical trials. Also strong interactions with pharmaceutical companies. Examples of recent publications: Zhang S, et al. Integration of Clinical Trial Spatial Multiomics Analysis and Virtual Clinical Trials Enables Immunotherapy Response Prediction and Biomarker Discovery. Cancer Res. 2024 84(16):2734-2748. doi: 10.1158/0008-5472.CAN-24-0943; Arulraj T, et al. Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade. Proc Natl Acad Sci U S A. 2024;121(45):e2410911121. doi: 10.1073/pnas.2410911121.
Specific skills include strong computational modeling from signaling pathways to tumor scales; knowledge of immunology and machine learning is a plus. Strong computer programming skills. Applicant must have a doctoral degree in biomedical engineering, chemical engineering, applied mathematics, computer science, pharmaceutical science or equivalent with a demonstrated record of innovative scientific accomplishments as evidenced by first-author papers published or accepted in premier journals. Qualified candidates must be able to work independently, demonstrate outstanding communication skills, have a strong commitment to science, and work well within a group.
Email CV and names of three references to: Dr. A.S. Popel, Dept. of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205. E-mail apopel@jhu.edu