We are seeking a motivated postdoc to join our growing team in the Yale University Center of Genomic Health and Department of Genetics. Our lab uses computational and experimental methods to understand how human genetic variation underlies health and disease, across rare and common phenotypes, with a focus on the mitochondrial genome. We also prioritize translating our research into practical tools that benefit research and clinical communities (e.g. Lake et al, Nature, 2024).
We are looking for a postdoc to spearhead computational projects that will develop and apply cutting-edge approaches for analyzing genetic variants in mitochondrial and nuclear genomes, and their role in disease. Individuals from diverse backgrounds are encouraged to apply.
The lab is located in the Yale School of Medicine which offers an outstanding training environment for postdoctoral scientists, with state-of-the-art research facilities and vast resources to support professional development. For more information about our lab, past publications and our research please see our website: www.thelakelab.org/
Responsibilities
• Use bioinformatic tools to analyze large-scale genomics datasets
• Develop and apply innovative methods for analyzing and classifying genetic variation
• Prepare high-impact manuscripts for publication and conference presentations
• Attend and present at lab meetings, journal clubs, and departmental seminars
• Contribute to the mentoring of students and junior scientists in the lab
• Assist in the preparation of grant proposals
• Maintain code and pipelines, and support lab operations as needed
• Positively contribute to lab culture
Mentoring & Professional Development
The lab has a strong emphasis on mentorship and values the opportunity to train future leaders in genetics and genomics. The PI will work with the successful candidate to develop and implement a mentorship plan tailor-made for their goals and interests. Mentorship will be provided for fellowship applications, manuscript writing, presentations, and independence.
The successful candidate will gain access to a range of career development opportunities at Yale. This includes seminars from internationally renowned researchers and ‘Meet the Speaker’ lunches, and professional development and networking activities including via the Yale Postdoctoral Association and Yale Office for Career Strategy.
Qualifications
Candidates should have or be close to obtaining a PhD in either genetics, genomics, computational biology, bioinformatics, or a related field.
Experience with programming languages (e.g. Python and R) and command line interface is required. Experience with one or more of the following is desired: large-scale genomic analyses, variant calling, high performance computing, cloud computing, machine learning methods, and or statistical genetics.
The ideal candidate will also demonstrate:
• Drive and initiative, and track record of impactful research outcomes
• Manuscripts published in peer-reviewed journals
• Ability to work both independently and as part of a team
• Eagerness to learn and establish new methods, and good problem-solving skills
• Excellent communication skills, both written and verbal
• Desire to contribute to the mentorship of students and junior scientists in the lab
• Experience in, or strong understanding of, human genetics or mitochondrial research.
Application Instructions
Please email the following to Dr. Nicole Lake at nicole.lake@yale.edu: (1) a cover letter summarizing your experiences, research interests, and career goals, and why you are interested in pursuing a postdoc in our lab, (2) your CV, including contact details of three references, and (3) when you are available to start, using the subject ‘Postdoc Application - Yale Lake Lab’.
Applications will be reviewed on a rolling basis starting December 16th, 2024, and continued until the position is filled. For any questions about the position, please email nicole.lake@yale.edu
Nicole J. Lake, Ph.D.
Assistant Professor of Genetics
Yale Center of Genomic Health
Yale University School of Medicine
www.thelakelab.org/
Yale University is an Affirmative Action/Equal Opportunity employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected veterans, and underrepresented minorities.