The Mellowes Center for Genomic Sciences and Precision Medicine (MC) is seeking an additional analyst to their highly productive Bioinformatics and Data Analytics Unit that services research partners. Genomics is key to modern research, and also revolutionizing the medical practice through the expansive use of high-throughput sequencing methods. Further, the MC is pioneering team science and dedicated to advancing research in genomics and epigenomics. Bioinformatics is the key to turning data into actionable knowledge through processing clinical and research Service Line samples, developing new testing methodologies, and to improving interpretation of genetic variants.
The successful candidate would be cross-trained across our bioinformatics research production service lines, including Exome-Seq, Whole Genome Sequencing (WGS), ChIP-Seq, RRBS, ATAC-Seq, RNA-Seq, scRNA-Seq, scATAC-Seq and Hi-C.They will also contribute to collaborative research projects for investigators within the Center. Therefore, prior experience in the analyses and visualization of NGS data types is required, and epigenetic data types preferred. We use code and task management systems; the candidate is expected to operate in these systems to facilitate team communication, project tracking, and process reporting. Prior experience in managing a portfolio of work through software systems is desired. This position has primary reponsibility for efficient and accurate completion of core services and research objectives of the Center. This position has secondary responsibility to contribute to the development of future bioinformatics and data science service lines. This Bioinformatics Analyst is expected to maintain current knowledge of the literature in bioinformatics, upholding and proactively improving analysis methods of the Center that underlie a wide variety of projects and publications.
Understands principles of NGS data, sequencing, and the interpretation of results. Independently provides troubleshooting for data generation and processing. Implements triaging and generates reports.
Develops, implements, and refines bioinformatic workflows and tools for analyzing and visualizing data including relevant QA/QC metrics.
Support and take lead on service lines that are not fully developed, as directed by the MC Director of Bioinformatics Shared Resources.
Leads the analysis for a portfolio of projects including implementing methods development plans. Presents regular project updates at meetings with collaborators or clients.
Adapts bioinformatics tools, visualization packages, and annotation resources for research projects to independently and accurately perform research analysis, such as workflow automation.
Maintains a professional level of knowledge of genetics and at least one focused topic related to the service lines that the candidate leads, to maintain state-of-the-art analyses and workflows.
Works with database and system administrators to implement and optimize methods for data input, storage, retirival, and reporting for APIs and data portals. Understands data security permissions management.
Operates, and troubleshoots, and improves analytic tools; notifies Supervisor when complex problems occur.
Partner with MCW IS to provide timely customer service support to service line clients, including data delivery and troubleshooting.
Minimum Education: M.S degree
Preferred Education: Ph.D degree
Prior Experience: 2 years or Thesis/Publications with direct relevance
Preferred Field of Study Bioinformatics, computational biology, molecular genetics, Machine Learning/AI, or comparable field