Principal Investigator & Assistant / Associate Professor

Institute for Research in Immunology and Cancer (IRIC) - Université de Montréal
Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal
Canada QC Montréal


This job posting is for a Principal Investigator & Assistant or Associate Professor position in the area of Drug discovery assisted by Artificial Intelligence (AI) at the Institute for Research in Immunology and Cancer (IRIC) of Université de Montréal in Montréal, Québec, Canada.

The Institute for Research in Immunology and Cancer (IRIC) in partnership with the Department of Biochemistry and Molecular Medicine of the Faculty of Medicine of Université de Montréal (UdeM) invites applications for a Principal Investigator and Assistant or Associate Professor position in the area of Machine Learning/Artificial Intelligence applied to the search for new treatments in human health, including mainly small molecules and possibly some aspects of chemical biology such as unnatural biopolymers (amino acids or nucleic acids) or natural products.

In particular, we are looking for an exceptional scientist to lead a research program in machine learning/artificial intelligence applied to drug discovery, which may include, but is not limited to: predictions of compound activity, predictions of compound physical/pharmaceutical properties, virtual screening of drug libraries, drug optimization, and design of retrosynthetic schemes. The candidate should be an experienced specialist in developing artificial intelligence algorithms, including, for example, deep learning networks, reinforcement learning, diffusion models, massive language models, or any other relevant techniques.

About Université de Montréal

Deeply rooted in Montréal and dedicated to its international mission, Université de Montréal is one of Canada's Top 100 Employers. Like the city whose name it bears, it is effervescent and multicultural. 

UdeM attracts over $500 million in research funding every year, making it one of the three university research hubs in Canada. It also ranks among the best universities worldwide and among the five best French-language universities. 

Through the achievements of the members of its community, UdeM participates in building today's and tomorrow's world. 

About IRIC

IRIC’s primary goal is to better understand the biological processes that contribute to cancer and identify ground-breaking avenues in the development of effective therapies. IRIC is located in a state-of-the-art building on the main campus of UdeM. It currently hosts 27 Principal Investigators and nearly 450 trainees, graduate students, postdoctoral fellows, research associates, and support staff. IRIC also comprises several cutting-edge core facilities, including Bioimaging, Biophysics & NMR, Flow Cytometry, Genomics, High-Throughput Screening (chemical, RNAi, and CRISPR), Bioinformatics, Histology, Medicinal Chemistry, Proteomics, and In Vivo Biology/Animal facility. Most importantly, IRIC houses one of the largest Drug Discovery Units in an academic setting in Canada. Its activities are led by a team of 65 expert chemists and biologists who have extensive drug discovery experience in an industrial setting. A collegial, dynamic, and curiosity-driven research environment is a defining feature of the Institute.

We offer competitive recruitment packages commensurate with experience and qualifications, a research-intensive environment, state-of-the-art facilities, and competitive graduate training programs. The new Principal Investigator will be appointed as a Faculty in the Department of Biochemistry and Molecular Medicine of the Faculty of Medicine of UdeM. The selected candidate will be considered for a philanthropic chair in AI applied to life sciences and may be eligible for a Canada Research Chair ( Access to IRIC’s core facilities and the extensive expertise of IRIC’s drug discovery unit will provide the candidate with a unique environment to validate the proposed algorithmic approaches. Within its ecosystem, the Université de Montréal is home to the Montreal Institute for Learning Algorithms (MILA) and the Institute for Data Valorization (IVADO), contributing to making Montreal a global hub for artificial intelligence.

The Department of Biochemistry and Molecular Medicine of the Faculty of Medicine includes 30 regular professors and more than 60 clinical or adjunct professors. Research teams address fundamental biomedical research questions in close connection with translational and clinical research conducted in the Faculty of Medicine network of affiliated hospital research centers and institutes. Through its cutting-edge teaching programs in biochemistry and bioinformatics, the Department supports the training of more than 350 undergraduate students and 200 graduate students. We are particularly interested in attracting colleagues who share our commitment to teaching, mentoring, and fostering a collaborative research environment that embraces both excellence and diversity. For more information, please visit the following websites:

- IRIC (
- Department of Biochemistry and Molecular Biology (
- Faculty of Medicine (
- Université de Montréal (

As a professor, you will have the opportunity to contribute to the promotion of excellence at IRIC and the Department of Biochemistry and Molecular Medicine of the Faculty of Medicine. Through your teaching and your research activities, you will also ensure the visibility of your discipline in addition to actively participating in the operation of a renowned institution. As such, you will be expected to:

- Emphasize the development of novel, state-of-the-art computing approaches rather than the application of existing tools;
- Collaborate on projects with large multidimensional datasets, so experience in integrating genomics, proteomics, and clinical data sets with drug screening would be an asset;
- Take part in academic-industry collaborations with biopharmaceutical partners;
- Develop an innovative, internationally recognized, financially independent research program;
- Supervise graduate students and postdoctoral fellows;
- Contribute to the teaching mission of the Department of Biochemistry and Molecular Medicine at the undergraduate, M.Sc. and Ph.D. levels;
- To succeed in this role, you will need to:

Additional information about the position :
- Application deadline: Until December 10 inclusively
- Salary: Université de Montréal offers competitive salaries and a full range of benefits
- Start date: As early as January 2024

Université de Montréal places the values of diversity, equity, and inclusion at the heart of each of its missions. Through its Equal Employment Opportunity Program (EEOP), the Université de Montréal invites women, Aboriginals, visible minorities, ethnic minorities, and people with limitations to submit their applications. During the recruitment process, our selection tools can be adapted in complete confidentiality to the needs of people living with limitations who request it. The University adopts a broad and inclusive definition of diversity that goes beyond applicable laws and encourages all qualified individuals, regardless of their characteristics, to apply. In accordance with Canadian immigration requirements, priority will be given to Canadian citizens and permanent residents. In order to measure the impact of its EDI actions, Université de Montréal collects data on applicants according to their identification with one of the groups targeted by the Equal Employment Opportunity Act, women, Aboriginal people, visible minorities, ethnic minorities, and persons with disabilities. To this end, we thank you for completing this self-identification questionnaire ("questionnaire d'auto-identification": The information you provide is confidential and will be shared only with those responsible for the EAP. If you wish, you may also indicate your membership in a targeted group in your letter of introduction, which will be reviewed by the selection committee and the assembly of peers during the evaluation of your file. According to the nomination procedures in effect at Université de Montréal, the members of the Assembly of Professors can consult all the application files. If you wish your application to remain confidential until the shortlist is established, please mention it.


- Hold a Ph.D. and demonstrate significant postdoctoral experience and productivity in a relevant area;
- Have an outstanding publication record;
- Have the potential to develop both internal and international collaborations;
- Demonstrate an ability to provide high-quality university-level education;
- An adequate knowledge of the French language (written and spoken) or a strong commitment to mastering the proficiency level required, in accordance with the Politique linguistique de l’Université de Montréal. An institutional learning support program is offered to all professors wishing to learn French or improve their communication skills.

Start date

January 08, 2024

How to Apply

You are invited to send your curriculum vitae, a letter of intent, a three-page long description of the proposed research program, as well as three (3) letters of recommendation from professors or hierarchical superiors to the attention of IRIC's Scientific Director: Dr. Philippe Roux (


Denise Van Rossum