Functional characterization of the snoRNome through network and integrative biology approaches

University of Sherbrooke
Biochemistry and Functional Genomics
Canada Quebec Sherbrooke
bioinfo-scottgroup.med.usherbrooke.ca/

Description

SnoRNAs are best known for their role in ribosomal RNA (rRNA) modification but the majority of snoRNAs have no known function or have other roles in gene expression regulation. We are using a multidisciplinary approach to uncover the function of snoRNAs by building networks of RNA and protein interactomes. Networks are built through cycles of computational prediction and experimental validation. The successful applicant will work with a team of experimental and computational biologists to integrate RNA-RNA and RNA-protein interactions, protein abundance, snoRNA abundance and mRNA abundance datasets to discover functional relationships and link it to cellular phenotypes.


Qualifications

Applicants should have a recent (<3 years) Ph.D. in quantitative sciences with proficiency in bioinformatics and transcriptomics. Candidates with a background in network biology, machine learning, and RNA biology will be preferentially considered. A good ability to use written and spoken English is required, French is optional. Only candidates with relevant publication record will be considered.


Start date

July 25, 2023

How to Apply

Email CV and motivation letter


Contact

Michelle Scott
michelle.scott@usherbrooke.ca