Human cells have the potential to make approximately 20,000 different proteins; but how and where are these proteins expressed? How do these proteins work together to enable life in individual cells and entire organisms, and how can their dysregulation contribute to human disease? In the Gygi lab we are developing state-of-the-art mass spectrometry and proteomics technology to address these kinds of scientific questions. This work depends on our computational pipeline that converts mass spectrometry data into quantitative datasets that may be mined for biological insight. We are seeking a software developer to maintain and further develop this platform to support both internal and external research efforts.
This position is a unique opportunity to develop software that will enable cutting-edge biomedical research as a member of a world-class mass spectrometry lab. We are looking for someone with a Bachelor’s or Master’s degree or equivalent experience in Computer Science, Computational Biology, Bioinformatics, Biochemistry, or related fields with a demonstrated interest in software development. The ideal candidate would be a full-stack web developer who is comfortable with Linux and can contribute to all stages of the development life cycle and who can design and manage relational databases. This work will include maintenance and development of an existing web application built with PHP in a LAMP environment. We also desire candidates with previous experience developing web-based interfaces for visualization and manipulation. While we do not expect applicants to have prior experience with mass spectrometry and proteomics, an interest in basic biology and a willingness to learn more about computational analysis of mass spectrometry data is highly desirable.
Responsibilities:
• Develop and maintain web-based software for analysis and visualization of large-scale proteomics datasets
• Implement novel tools and algorithms for analysis and visualization of proteomics datasets independently and in collaboration with Gygi lab members
• Provide technical support for internal and external software users
• Administer lab servers
• Maintain lab websites
Qualifications:
• Experience with full-stack web development
• Languages: PHP, HTML, CSS, Javascript, C++, Python (multiple languages are optional, but encouraged)
• R and R-Shiny (Optional, but encouraged)
• Database: MySQL
• System: Linux, Unix
• Version Control: Git
• Testing and Deployment: Jenkins, Docker, RPM/Debian packages
• Basic familiarity with biology and chemistry (optional)
• Knowledge of mass spectrometry, proteomics, and/or bioinformatics (optional)
Education Requirements:
• Bachelor’s or Master’s degree required in Computer Science, Computational Biology/Bioinformatics or similar
• We will also consider applicants with degrees in biology, biochemistry, chemistry, and related fields with demonstrated interest in software development
Benefits:
• Benefits are standard for Harvard Medical School Employees
Send resume and cover letter to the e-mail listed above.