Postdoc in single-cell omics data analysis for cancer immunotherapy and treatment resistance

OREGON HEALTH&SCIENCE UNIVERSITY
Biomedical Engineering Department
United States OR Portland
xiazlab.org

Description

The Computational Biology Program and Knight Cancer Institute at Oregon Health & Science University (OHSU) invite applications for Postdocs and Ph.D. students in the areas of computational biology and bioinformatics. We seek motivated applicants to perform big data-driven translational research in a highly interdisciplinary and collaborative environment to advance the progress in both methodology and biology. Our lab has published papers with leading roles in Nature, Nature Biotechnology, Nature Communications, PNAS, Clinical Cancer Research, Molecular Cells. At OHSU, we are dedicated to performing translational research, inspired by Dr. Brian Druker’s pioneering work in Gleevec for cancer treatment. Our previous trainees have published first-author papers in Nature, and Nature Biotechnology, and found their dream jobs in industry (Genentech and BMS) or academia (Professor of Mathematics).

The positions have the potential to be co-mentored with Dr. Gordon Mills to analyze massive single-cell clinical data generated from the SMMART precision medicine program.

Research projects:
1. Developing new methods for Single-cell data analysis (Nature Biotechnology, 2021)
2. Cancer treatment resistance(Clinical Cancer Research, 2020, 2021; PNAS, 2020; Nature Communications, 2022)
3. Immunotherapy (Nature, 2022)
4. Machine learning/deep learning for public omics-data analysis

About OHSU
OHSU is ranked as one of the nation’s top 30 medical schools. With long-term resource commitments, such as the $1 billion Knight cancer “challenge”, substantial resource is provided to support state-of-the-art computational research, including a world-class exascale supercomputing cluster, close interactions and resource commitments by leading technology companies such as Intel, tight integration with clinical and basic research programs across campus. OHSU Knight Cancer Institute, directed by Dr. Brian Druker, is an NCI comprehensive cancer center and is named after Nike co-founder Phil Knight.


Qualifications

We are looking for:
• The applicants have degrees in Computer Science, Computational Biology, Statistics, Genetics, Data Science, Bioinformatics, Biostatistics, Mathematics, or related fields.
• First (or co-first) author in one or more peer-reviewed scientific publication
• Programming proficiency in R and Python;
• Experience in sequencing data analysis like RNA-seq, ATAC-seq and single-cell data
• Experience in machine learning and statistics.


Start date

As soon as possible

How to Apply

If you are interested, please send your CV to Zheng Xia: xiaz@ohsu.edu


Contact

Zheng Xia
xiaz@ohsu.edu