The 3D Chromatin Genomics Lab at JAX-GM is seeking to appoint a postdoctoral associate to participate in research directed toward elucidating the structures and dynamics of complex genomes. For more on the Wei Lab’s research and goals, visit: www.jax.org/research-and-faculty/faculty/chia-lin-wei
Postdoctoral Positions in Three-dimensional (3D) Chromatin Genomics
Chromatin interactions and its 3D structure play a major role in regulating gene expression by bringing together regulatory elements that are distal on the linear genome in close physical proximity with each other. Our Lab have pioneered genomic technologies for genome-wide profiling chromatin interactions. We are seeking enthusiastic, highly skilled computational and experimental post-docs to generate and analyze human chromatin interaction datasets in integration with other genomics and genetics datasets.
We are seeking postdoctoral researchers to develop computational and genomic approaches for understanding 3D genome biology under the light of diverse genomic and genetic information. We are seeking self-motivated, independent individuals who are interested in building their own career paths; however, postdoctoral fellows are expected to coordinate with and report to the PI responsible for the research area(s) addressed by their project. The fellows will develop research projects in one or more areas of focus:
• 3D genome mapping and imaging technologies
• Application of nano-engineering toward genomic methodologies
• Computational modeling of 3D genome architectures
• Building regulatory networks at multiple layers including gene expression, epigenetic, and chromatin data
• Integrating regulatory interactions with genetic data
• Mining and aligning chromatin interaction datasets in diverse human cell types
• Functional perturbation of topological elements
Our Postdoctoral Associates enjoy distinct advantages, including:
• Advanced research in 3D epigenome technology and Biology.
• A uniquely collaborative environment that fosters interdisciplinary “team science” without departmental barriers
• Unparalleled genomic resources and superior research support services
• Close interaction with our award-winning faculty members
• Partnerships with leading universities and medical centers
• Numerous courses and conferences focused on genetics, genomics and biomedicine
• Exceptional benefits, ample time off and other valuable programs
• Working for an institution that has repeatedly been voted among the top 15 “Best Places to work in Academia” in the world by readers of The Scientist
• PhD (or nearing completion of PhD degree)
• Background in human genetics or genomics and disease research
• Publications (1st author highly advantageous)
For computational postdocs desired attributes include:
• Strong problem-solving skills, creative thinking, and enthusiastic about science
• Excellent communication skills and fully fluent spoken and written English
• Familiarity with next generation sequencing data sets and pre-processing
• Excellent programming skills,
• Familiarity with network building, mining, alignment algorithms
• Familiarity with bioinformatics resources, i.e., UCSC genome browser, NCBI.
For experimental postdocs desired attributes include:
• Strong problem-solving skills, creative thinking, and enthusiastic about science
• Excellent communication skills and fully fluent spoken and written English
• Familiarity with next generation sequencing data sets and data generation
• PhD in a genomics/genetics/biology or another relevant field
• Expertise in cellular and molecular biology techniques