Postdoctoral fellowship position at the FDA: Modeling and simulation of CAR T cell therapy

United States Maryland Silver Spring


A research opportunity is available with the Office of Biostatistics and Epidemiology (OBE) at the Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA) in Silver Spring, Maryland.

The successful candidate will participate in the development of a quantitative key event relationships model to simulate and predict immune responses of Chimeric Antigen Receptor (CAR) T cells. The end goal of this project is the development of a computational tool to enhance efficacy and safety evaluation of current and next-generation of engineered therapeutic products, leading to personalized, optimal treatment regimens for patients undergoing CAR T cell therapy. Under the guidance of a mentor, the participant will help develop and apply novel techniques to model and simulate interactive cellular components of CAR T Cells, as well as perform literature reviews, data collection/database curation, model development, presentation of research results, and preparation of scientific manuscripts.


The Homeland Security Presidential Directive-12 (HSPD-12) mandates a background check be completed for both U.S. Citizens and foreign nationals. Foreign nationals must have resided in the U.S. for at least three (3) of the past five (5) years in order for FDA to be able to complete a background check.

The qualified candidate should have received a doctoral degree in one of the relevant fields, or be currently pursuing the degree and will reach completion by June 1, 2019. Degree must have been received within five years of the appointment start date.

Preferred skills/experience:
Knowledge of immunology, modeling and programming skills
Experience with differential equations
Excellent written and oral communication skills
Solid background and skills in both biology and computing science

Start date

As soon as possible

Start date

To be determined

How to Apply

Highly motivated candidates should apply through (Reference Code: FDA-CBER-2019-0022)