immune profiling of human response to vaccination

University of Pennsylvania
United States PA Philadelphia


The major interest of our lab is to understand how cumulative exposure to environmental antigens impact response to vaccines/infections. We conduct patient-directed research and utilize a number of high-dimensional and high-throughput technologies to directly interrogate the functional states of relevant T cells directly from human biospecimens. We are looking for a talented individual to lead the analyses on the immune profiles of vaccine induced T cell response. By integrating T cell receptor, transcriptomic, proteomic, and epigenetic datasets generated from vaccine-specific T cells, our goal is to achieve a global understanding on how basal memory state impacts protective immunity in humans.


Successful candidates will hold a PhD in Bioinformatics, Computational Biology, Computer Science, Biology, or other disciplines providing training and experience in computer science and an understanding of biology. Strong programming experience and familiarity with statistics and R programing is required. High level of independence is expected. Excellent organization and time management skills are required as well as a strong interpersonal skills and the ability to effectively interact with all members of the lab and external collaborators.

Start date

As soon as possible

Start date

To be determined

How to Apply

Please send your curriculum vitae and a cover letter with a statement of research and technical experience by e-mail to Dr. Laura Su at


laura su