Join a Team that Lives to Improve Lives
People come to Genentech from across disciplines and across the world to solve our most challenging medical conditions. You’ll find inspiration in our passion for biotechnology, our purpose to positively impact the lives of millions of patients and our dedication to our people. Joining Genentech means being part of a tradition of inquiry that will change the world. It means embracing our failures as much as our successes. It requires a willingness to look beyond the edge of what's possible. And a focus on doing the day-to-day work that makes great science happen.
The following opportunity exists in our South San Francisco, CA headquarters:
Scientist, Oncology Biomarker Development
Description
We seek a highly motivated Scientist within Development Sciences to support biomarker and diagnostic development efforts focusing on Genentech's Oncology pipeline. The incumbent will apply advanced bioinformatics and data analysis skills in collaboration with a group of biomarker scientists to execute on predictive and pharmacodynamic biomarker, and companion diagnostic strategies for programs in clinical development.
For this particular position, a strong background in cancer biology and bioinformatics or biostatistics, evidenced by peer reviewed publications in top tier journals, would be an important asset. The successful candidate is expected to effectively interact with cross functional teams; analyze data supporting innovative clinical development programs and publications focused on biomarker or disease research; interact with key collaborators and investigators; and promote collaborative efforts to advance biomarker sciences.
As a Scientist, you are expected to:
-Manage and support analysis of large clinical biomarker datasets including NGS-based DNA and RNA testing
-Effectively manage scientific collaborations, both internal and external
-Drive scientific and technical innovation collaboratively with other members of the department
-Support development and execution of exploratory biomarker and companion diagnostic strategies for multiple projects
-Support publications in high quality scientific, technical or medical journals
-Represent the biomarker team externally through interactions with our key investigators
-Participate and thrive in an interactive, team oriented culture
-PhD degree in a relevant scientific field (e.g., molecular biology, cancer biology, genomics, or bioinformatics)
-Minimum of 2 years postdoctoral experience in basic or translational research either in an academic or industry setting
-Strong bioinformatics programming skills (e.g., using R or Python) and familiarity with the Unix operating system. Experience with Bioconductor is preferred.
-Experience analyzing and interpreting high throughput genomic data, especially whole exome, targeted NGS, and whole transcriptome sequencing, is highly desired
-NGS assay or platform development expertise, particularly with clinical sequencing applications, would be highly beneficial
-Experience in clinical drug development is beneficial, including understanding of critical development functions, e.g., biomarker development, operations, and biostatistics.
-Knowledge and understanding of current methods being used to assess tumor biology in the clinical setting, and familiarity with systems biology tools would be advantageous
www.gene.com/careers/detail/201809-120490/Scientist-Oncology-Biomarker-Development