Postdoc position: The logic of gene regulation by enhancer elements

MRC London Institute of Medical Sciences, Imperial College London
Functional Gene Control group, Epigenetics and Integrative Biology sections
United Kingdom London
functionalgenecontrol.group

Description

A 3-year postdoctoral position is open in the Functional Gene Control group at MRC London Institute for Medical Sciences (LMS) led by Dr Mikhail Spivakov (lms.mrc.ac.uk/research-group/functional-gene-control/ and functionalgenecontrol.group). We combine experimental and computational approaches to study the logic of gene regulation, with a particular emphasis on the function of DNA elements such as enhancers in gene regulatory networks and on human primary cells as experimental systems. Examples of our recent work include Freire-Pritchett et al., eLife 2017, Javierre et al., Cell 2016, and the Chicago R package for Capture Hi-C analysis (Cairns et al., Genome Biol 2016).

You will join an international, multidisciplinary team within a collaborative and stimulating research environment, with strong links with other groups at the LMS and beyond.


Qualifications

You will have a PhD, a strong background in a biomedical science or quantitative discipline (mathematics, statistics, physics, computer science), as well as prior experience in generating and/or interrogating data from high-throughput genomics assays. Competence in the analysis of chromosomal interactions and cis-regulatory networks is particularly relevant, and a track record in devising novel experimental and/or computational techniques is desirable. The ideal applicant will have a dual wet- and dry-lab expertise, but strong candidates from either one of these backgrounds are also encouraged to apply.


Start date

As soon as possible

How to Apply

For full details of this post and to complete an online application, visit mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1042 and upload your CV, names and contacts of two scientific references along with a covering letter stating why you are applying for this role (providing evidence against the requirements of the job and your motivation). Please quote reference number LMS – 926.

Informal inquiries can be addressed to Dr Mikhail Spivakov (mikhail.spivakov@lms.mrc.ac.uk).

Closing date: 27 October 2018