The Ke Lab is seeking a postdoctoral associate at The Jackson Laboratory in Bar Harbor, Maine. The Ke Lab focuses on RNA, a central node of genetic information flow from DNA to protein (www.jax.org/research-and-faculty/faculty/shengdong-ke). Malfunction of RNAs leads to many human diseases, including neurological diseases and cancer. To thoroughly address fundamental molecular mechanism of RNA, the Ke lab utilizes multidisciplinary approaches, including cutting-edge computational biology, biochemistry, innovative bio-technologies, genetics and molecular biology. We are especially interested in m6A RNA biology: 1) the fundamental mechanism of m6A RNA biology, and 2) the biological effects of m6A regulation in nerve system, using mouse and human iPS models. (References: 1] Ke, S. et al. m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover, Genes & Development 2017, 31: 990-1006; 2] Ke, S. et al. A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation, Genes & Development 2015, 29:2037-53.)
Qualified candidates will be self-motivated and career oriented individuals, have a genuine interest in addressing complex biological questions, and have a Ph.D. or MD. degree with background in one of the following areas, including computational biology, biochemistry, molecular biology, biotechnology, neurosciences, immunology, stem cell, or cancer biology. Skills in quantitative programming or biochemistry are preferred but not required.
Apply online at www.jax.org/postdoc or email CV to postdoc@jax.org and include Job ID number in subject line