The Obeng Laboratory is seeking creative and highly motivated candidates for a fully supported postdoctoral fellowship studying the pathogenesis of myeloid malignancies. The major interests of the lab are determining how mutations in components of the mRNA spliceosome and epigenetic regulators cooperate to cause clonal hematopoiesis and leukemia, in addition to identifying and studying novel treatments that selectively target malignant clones.
You will have the opportunity to develop and lead projects using several cutting-edge model systems including:
•Isogenic immortalized cell lines generated using CRISPR-Cas gene editing
•Novel xenograft and transgenic in vivo systems
•Primary patient samples
In this position, you will gain extensive experience and training in genomics, stem cell biology, and pre-clinical study development.
Successful applicants will have a Ph.D. in molecular biology, cell biology, genetics or a related field; a strong publication record; and excellent communication skills. To succeed in this position, applicants must have a strong cell and molecular biology background and an interest in working with in vivo model systems. Applicants with expertise in genome editing, computational biology, and working with hematopoietic stem cells are encouraged to apply.
Email CV to postdoc@stjude.org