Postdoctoral bioinformatics research in single-cell biology

The Children's Hospital of Philadelphia / University of Pennsylvania
Department of Biomedical and Health Informatics
United States Pennsylvania Philadelphia
careers.chop.edu/job/Philadelphia-Res-Post-Doc-Fellow-PA-19146/469577300/

Description

Postdoctoral positions in quantitative computer science, bioinformatics, computational biology and single-cell analysis are open in the Taylor research group at The Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania (Penn).

Our research goals are to understand cellular function in human genetic diseases of metabolism. Current projects include quantifying single-cell expression from tissues with mutant mitochondria; analysis of translational initiation in prokaryotic systems; analysis of single-cell differences between children and adults; computational analyses of cell state from single-cell data. Some examples of relevant research are published in Mol Cell (2015, 2018), Science (2016), PLoS Genetics(2015) and PNAS (2016).

Postdoctoral fellows in these positions will help lead the development of single-cell analysis methods towards understanding metabolism and disease and also take part in projects featuring massively parallel data from eukaryotic and Candidates must have a terminal degree (PhD) with a focus in a quantitative science, with strong computational experience, ideally with some biology training. Strong skills in Python programming are highly preferred. The successful candidate will have some familiarity or strong interest in analysis of complex or highly dimensional data, statistics and statistical methods including clustering or machine learning, and information theory.

It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall translational research goals of the project and the research group. Postdocs will be expected to participate in project planning, recording and interpretation/evaluation of data, and communication of results. The successful candidate is also expected to demonstrate basic scientific knowledge of biology of cells and molecules.

Postdocs will also be expected to acquire technical and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and travel for presentations at national and international meetings. Postdoctoral fellows also may be required to develop new methods and protocols for research, and assist with the development of other research projects in the lab.

The Bioinformatics group in DBHI led by Dr. Taylor has over twenty bioinformatics professionals leading research on over 40 biomedical analysis projects. Postdoctoral fellows at CHOP receive mentored translational science and bioinformatics training in a rich scientific environment that includes both CHOP and University of Pennsylvania research communities, as well as exposure to several large multi-institutional collaborations. Postdoctoral fellows training in DBHI will serve to extend, refine and enhance skills necessary for professional and career development in translational bioinformatics research, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities.


All CHOP employees who work in a patient building or who provide patient care are required to receive an annual influenza vaccine unless they are granted a medical or religious exemption.

Children's Hospital of Philadelphia is committed to providing a safe and healthy environment for its patients, family members, visitors and employees. In an effort to achieve this goal, employment at Children's Hospital of Philadelphia, other than for positions with regularly scheduled hours in New Jersey, is contingent upon an attestation that the job applicant does not use tobacco products or nicotine in any form and a negative nicotine screen (the latter occurs after a job offer).

Children's Hospital of Philadelphia is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability or protected veteran status.

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CHOP Careers Contact
Talent Acquisition
2716 South Street, 6th Floor
Philadelphia, PA 19146
Phone: 866-820-9288
Email:TalentAcquisition@email.chop.edu


Qualifications

Required Education and Experience

A terminal degree PhD, MD, DVM, etc.
According to the CMS (Centers for Medicaid and Medicare Services) a copy of diploma or transcript is required as proof of academic achievement for all non-laboratory personnel performing non-waived POC testing

Preferred Education, Experience & Cert/Lic
PhD in relevant fields for computational biology, such as computational sciences, biophysics, statistics, mathematics, engineering, genomics/genetics, biology, or other quantitative fields.

Additional Technical Requirements

Proficiency in R or similar commonly used statistical languages
Basic proficiency with Python, Perl, or other languages
UNIX/LINUX and high performance computing experience
Values research integrity and collaborative research
Strong research skills
Effective problem solving/critical thinking skills
Ability to work independently and with a strong work ethic
High level of motivation
Excellent communication/interpersonal skills
Ability to exercise discretion and judgment


Start date

As soon as possible

How to Apply

Please visit our URL: careers.chop.edu/job/Philadelphia-Res-Post-Doc-Fellow-PA-19146/469577300/