Clinical Cancer Genomics

The Ohio State University
Comprehensive Cancer Center
United States Ohio Columbus
www.precisioncancermedicine.osu.edu/

Description

Sameek Roychowdhury’s lab team in the Division of Medical Oncology and the Comprehensive Cancer Center at the Ohio State University focuses on the application of genomics for clinical oncology. Areas of research focus include:
1) Development of analytically validated targeted DNAseq and RNAseq assays in a CLIA-certified Cancer Genomics Laboratory to enable molecular enrichment of patients to trials,
2) Genomics-driven clinical trials,
3) Rapid research autopsy to study tumor heterogeneity in patients,
4) Next generation sequencing strategies including whole exome, RNAseq, and targeted capture sequencing to a) study drug resistance, b) contribute to target discovery, c) study immunology and genomics, and d) molecularly characterize exceptional responders.

The Team utilizes next generation sequencing strategies including exome, RNAseq, and targeted capture sequencing for the development of genomics-driven clinical trials and characterization of novel genomic targets and drug resistance. The Team also runs a CLIA-certified Cancer Genomics Lab that develops custom NGS Assays for clinical trial eligibility---results can have an immediate impact on patients with cancer. The Team runs a study “Precision Cancer Medicine for Advanced Cancer Through High-throughput Sequencing” (OSU-13035) that evaluates individual patients with advanced cancer considering clinical trials, and seeks to identify “driving” mutations that provide molecular eligibility for novel molecularly targeted therapies in development at Ohio State.

Our Team consists of experts in cancer biology, genomics, computational biology, molecular diagnostics, pathology, medical oncology, and experimental therapeutics. To accomplish our Mission, we promote an environment for Teamwork and Training for all Team Members at every stage of training. Due to the inter-disciplinary professional work environment of clinical tumor sequencing, we seek an applicant with good communication skills and experience working as part of a Team.

Requirements:
The ideal candidate should hold a masters degree or doctorate in Computer Science or Bioinformatics or Computation Biology.
Experience with next-generation sequencing is highly desired.
Experience with high level programming languages (e.g. Python, R, Perl, C++) required.
Experience with supercomputing preferable and the candidate should be comfortable working on Linux/Unix environment.
Experience with manipulation, interpretation and innovative analysis of large biological datasets, preferred.

Visit us at: www.precisioncancermedicine.osu.edu/about-lab
Join our Team
Interested applicants should contact us at Sameek.roychowdhury@osumc.edu and include the following:
1. Areas of research interest in our Lab
2. Brief cover letter
3. CV (Curriculum Vitae)
We will be conducting interviews on-site at GLBIO 2017 in Chicago (May 15-17, 2017). Please contact us to arrange a time to meet in person!



Qualifications


Start date

To be determined

How to Apply

Interested applicants should contact us at Sameek.roychowdhury@osumc.edu and include the following:
1. Areas of research interest in our Lab
2. Brief cover letter
3. CV (Curriculum Vitae)
We will be conducting interviews on-site at GLBIO 2017 in Chicago (May 15-17, 2017). Please contact us to arrange a time to meet in person!

Sameek.roychowdhury@osumc.edu


Contact

Sameek Roychowdhury
Sameek.roychowdhury@osumc.edu