Bioinformatics Scientist and Software Engineer

University Clinic of Cologne
Department of Virology
Germany Northrhine-Westphali Cologne


The Institute for Virology (Director: Univ.-Prof. Dr. Florian Klein) specializes in diagnostics and research pertaining to human pathogenic viruses. We apply a wide spectrum of molecular biological and bioinformatics techniques. Research topics include the identification and assessment of the development of viral resistance as well as research on new vaccination and therapeutic strategies. This research is performed in the Laboratory for Resistance Analysis directed by Dr. Rolf Kaiser. In collaboration with the Max Planck Institute for Informatics in Saarbrücken we have developed algorithms and implemented software (geno2pheno) that is used internationally and facilitates bioinformatics analyses of viral resistance for HIV as well as the hepatitis C and hepatitis B viruses. Directed by Prof. Dr. Thomas Lengauer, who directed the development of the server and who is currently affiliated with our Institute we are continuing our research on the respective methods and applications. Furthermore we are extending our research to bacterial infections and cancer.

» Your tasks
- Research on bioinformatics methods for processing and analyzing comprehensive genomic and clinical datasets (viral and bacterial infections)
- Support of porting the geno2pheno server from Saarbrücken to the University of Cologne and advancing the respective methods and software
- Administration and continuing development of the software that is provided by the Laboratory for Resistance Analysis
- Development, implementation and application of corresponding software

The position has a three-year term. There is the possibility of subsequent permanent employment after successful
evaluation. The salary will be based on TV-L until EG 14, depending on requirements.

You will work in a highly interdisciplinary environment that is internationally excellently interconnected and provides opportunities for innovative research on patient-related and medically highly relevant topics. Collaboration with research groups in medicine, computational biology and computer science at Cologne University are existing or available. Your research will uniquely combine basic research on computational methods with medical applications. Perspectives for scientific advancement towards PhD or beyond are included in the profile of the position.

Application materials include letter of motivation, CV, documents and transcripts, publication list, research statement (detailed description of previous experiences in research and programming as well as sketch of research perspectives) and names of two references – or employer’s reference letters, also from recent times, for applicants from an industrial background. We ask for supplying complete applications with all requested documents.


- Master or PhD in bioinformatics/computational biology, biostatistics, computer science or a closely related field
- Extensive knowledge and experience with programming languages and environments (e.g. R, Python, Perl, PHP, C++, Java, Javascript, Oracle, Webserver), to be documented via central contributions to larger programming projects (programming experience within curricular courses or practicals is not sufficient)
- Proactive team player with excellent communication and writing skills
- Extensive knowledge and experience with methods of statistics and statistical learning including their mathematical foundations

Start date

As soon as possible

How to Apply

Online through the job portal link displayed in the job announcement at


Thomas Lengauer

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