Exact knowledge of tumor etiology is required to design models for preclinical testing and personalization of cancer therapies. However, tissue and developmental stage of origin remain an enigma for many childhood cancers, severely hampering progress in pediatric cancer research and treatment.
Funded by an international organization, St. Anna Children´s Cancer Research Institute (CCRI), has joined forces with the Medical University of Vienna (MUW) and the University of Natural Resources and Life Sciences (BOKU) to track the origins of pediatric bone sarcomas using developmental and trans-species genomics. The interdisciplinary consortium is located in Vienna, the world’s most livable city and one of Europe’s most important places for biomedical research and life sciences.
We are looking for computational biologists at post-doctoral level who want to contribute to solving one of the most mysterious puzzles in pediatric oncology by employing their skills in single-cell analysis at the interface of developmental and cancer biology.
As a postdoc, you will:
* Join a cooperative team embedded in a strong, well-funded consortium. We are dedicated to support your personal and professional development
* Be the computational mastermind of the consortium. Your work will critically shape this project, with plenty of room to bring in and develop your own ideas
* Analyze lots of functional genomics data (primarily single-cell RNA-seq, ATAC-seq) using established workflows and your own algorithms
* Interpret, present, and discuss your results frequently with other consortium members, at local meetings, and at international conferences
* Write and review papers, apply for fellowships and grants, contribute to the supervision of junior group members
Our offer:
* A four-years-contract for a challenging position in a meaningful, inspiring, and international environment
* An outstanding working atmosphere in a strong team with excellent research and development opportunities
* Access to state-of-the-art infrastructure and personal computing equipment
* Flexible working hours, discounted lunch in our canteen and other great benefits
* Great location in the center of Vienna, a capital of biomedical research in Europe with excellent quality of life
* A fair and attractive salary package according to the Austrian Science Fund FWF (www.fwf.ac.at/en/research-funding/personnel-costs/)
Who we are:
The St. Anna Children’s Cancer Research Institute (CCRI), located in the center of Vienna, the world’s most livable city and one of Europe’s most important places for biomedical research and life sciences, is an international and multidisciplinary competence center striving to improve treatment of children and adolescents with cancer by connecting translational and clinical research with open-minded exploration of basic disease mechanisms. Through close cooperation between clinic and research, the CCRI provides an ideal environment for cutting-edge research and its translation into clinical practice. To achieve our ultimate goal of advancing the well-being of patients, the CCRI constantly pushes scientific boundaries and strongly promotes close collaboration and exchange with external institutions like the Medical University of Vienna, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) and the Institute of Molecular Pathology (IMP).
You will join the Developmental Cancer Genomics Group at CCRI. The focus of the group is on understanding developmental processes in cancer biology by employing an integrative approach that combines developmental biology with functional genomics, data analytics, and mathematics.
The CCRI is an equal opportunity employer. We value diversity and are committed to providing a work environment of mutual respect to everyone without regard to race, ethnicity, religion, national origin, age, gender identity or expression, disability, or any other characteristic protected by applicable laws, regulations and ordinances.
For more information visit: www.ccri.at/, or cancerbits.github.io/
Your profile:
* PhD in a relevant subject (bioinformatics, genomics, molecular biology, cancer, etc.)
* At least one first-author publication in a reputable journal
* Good programming skills (R or Python); solid understanding of statistics
* Extensive experience with *-omics data analysis (e.g., RNA-seq, ATAC-seq). Experience with single-cell analyses highly desirable
* Good knowledge of molecular biology and genomics. Experience in cancer or developmental biology is a plus
* Excellent verbal and written communication skills in English (German not required)
* An exceptional level of enthusiasm, determination, and creativity
Please send your application via email to Dr. Florian Halbritter, application@ccri.at. Applications should contain your Curriculum Vitae, a motivation letter (in English only), list of publications (please briefly explain your top contributions), and the contact details of three references. Applications will be reviewed on a rolling basis. The position shall remain open until a suitable candidate is found. The prospective start date for the position is in spring 2021.